Remember that "Marvel-related series" Joss Whedon was meant to be developing for ABC? Turns out it's a S.H.I.E.L.D. series, and Whedon is already preparing the pilot, so you can stop reminding him how quickly Dollhouse flopped.
Deadline reports the show's opener will likely be directed by Whedon, who's also co-writing with Dr. Horrible and Dollhouse writers Maurissa Tancharoen and Jed Whedon (Joss's straw hat and overalls-wearing country brother), with all three executive producing alongside Jeffrey Bell and Marvel TV's Jeph Loeb.
In the Marvel movie universe, S.H.I.E.L.D. stands for "Strategic Homeland Intervention, Enforcement and Logistics Division." It's the covert law-enforcement agency that employs Scarlett Johansson's Black Widow, Cobie Smulders' Marie Hill, Jeremy Renner's Hawkeye, Clark Gregg's Phil Coulson, and eventually, in an unofficial capacity, the entire Avengers team under the watchful, remaining eye of Samuel L. Jackson's Nick Fury. It's thus far unclear if any of that cast will transition into the series, but considering how vital director Fury is to the agency--and how much Samuel L. Jackson really loves a paycheck (see: Snakes on a Plane, this rotten thing)--I wouldn't be entirely surprised if Jackson agrees to show up every now and then. Or if he won't, well, then there's always a Plan B that has absolutely nothing going on now he's finished shooting The Celebrity Apprentice Australia...