Long in development under the title Kitchen Sink, Freaks of Nature indeed takes such an approach to genre filmmaking. The teen comedy centers on a small Ohio town where humans, vampires, zombies, and comedy ringers all coexist in a delicate, blood-splattered balance. An alien invasion added to that ends up being a bit much, though, so a teen human, teen vampire, and teen zombie team up (alongside Bob Odenkirk, Patton Oswalt, Denis Leary, Keegan-Michael Key, Ian Roberts, and more) to fight off the foreign invaders--raising the question, for the first time since Teen Wolf Too, should there not be a teen wolf, too? I guess they had to save something for the sequel.
Here's the red-band, NSFW trailer: